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どうしたの
1. what's the matter?, what's wrong?
2. what happened (to) ...?, what have you done (with) ...?, where is ...?
tbd
は
1. indicates sentence topic
2. indicates contrast with another option (stated or unstated)
3. adds emphasis
指示句子的主题;表示与另一选项(无论是否明确提及)形成对比;表示强调